Symbol
Name
ID

Ank3
ankyrin 3, epithelial
MGI:88026

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Microcephaly

Spasticity

EEG abnormality

Delayed speech and language development

Delusion

Schizophrenia

Hallucinations

Negativism

Aggressive behavior

Hyperactivity

Bruxism

Social and occupational deterioration

Intellectual disability

Intellectual disability, moderate

Sleep abnormality

Global developmental delay

Seizure

Disease(s) Associated with ANK3

autosomal recessive intellectual developmental disorder 37

schizophrenia

Mouse Phenotypes

convulsive seizures

abnormal hippocampus neuron morphology

Purkinje cell degeneration

abnormal Purkinje cell axon morphology

decreased Purkinje cell number

thin cerebellar molecular layer

small cerebellum

abnormal axon morphology

abnormal axon initial segment morphology

abnormal node of Ranvier morphology

abnormal paranodal axoglial junction morphology

abnormal nervous system electrophysiology

abnormal action potential

impaired ability to fire action potentials

abnormal brain wave pattern

Availability

Mouse Genotype

Ank3^tm1Bnt/Ank3^tm1Bnt

Ank3^tm2.1Bnt/Ank3^tm2.1Bnt
Tg(Nes-cre)1Kln/? (conditional)

Ank3^tm3Bnt/Ank3^tm3Bnt
Tg(Nes-cre)1Kln/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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